medparasitologyМедицинская паразитология и паразитарные болезниMedical Parasitology and Parasitic Diseases0025-83262713-1777Научно-образовательный паразитологический центр им. П.Г. Сергиева10.33092/0025-8326mp2026.2.45-51medparasitology-152Research ArticleОБЗОРREVIEWИзучение биоэкологии мух-гиппобосцид (Diptera: Hippoboscidae) в целях поиска антимикробных пептидов для борьбы с антибиотикорезистентными патогенамиStudy of the bioecology of hippoboscid flies (Diptera: Hippoboscidae) to identify antimicrobial peptides for combating antibiotic-resistant pathogensГрицюкО. В.GritsyukO. V.РаковаВ. М.RakovaV. M.МетлаА. А.MetlaA. A.ШепелеваВ. Д.ShepelevaV. D.ЛавинскаяА. Р.LavinskayaA. R.ФГБУ «ЦСП» ФМБА РоссииРоссияFSBI CSP of FMBA of RussiaRussian FederationФГАОУ ВО МГАВМиБ им. К.И. СкрябинаРоссияFSEI HPE MSAVMB named after K.I. SkryabinRussian Federation202611092026024551Copyright © Научно-образовательный паразитологический центр им. П.Г. Сергиева, 20262026Научно-образовательный паразитологический центр им. П.Г. СергиеваНаучно-образовательный паразитологический центр им. П.Г. Сергиеваhttps://www.medparasitology.com/jour/about/submissions#copyrightNoticehttps://www.medparasitology.com/jour/article/view/152

Млекопитающие и птицы являются основными хозяевами для многочисленных видов мух-кровососок (Diptera: Hippoboscidae). Данные эктопаразиты участвуют в циркуляции широкого спектра патогенов, включая бактерий (Borrelia, Bartonella, Rickettsia, Anaplasma, Ehrlichia), простейших (Trypanosoma, Theileria, Piroplasmida, Haemosporida) и вирусов (в частности, вирус Западного Нила). Гиппобосциды являются облигатными эктопаразитами и длительный контакт с патогенами хозяев в ходе эволюции сформировал в их организме высокоэффективные «природные антибиотики» - антимикробные пептиды (АМП). В статье обобщены актуальные сведения о патогенах, ассоциированных с гиппобосцидами, обоснована необходимость дальнейшего изучения биоэкологических аспектов: видового состава, распределения и численности кровососок. Лабораторный мониторинг данной группы насекомых важен для понимания механизмов сохранения и распространения природно-очаговых инфекций, опасных для человека и животных, так же уделено внимание антимикробным пептидам (АМП) насекомых и их активности в отношении антибиотикорезистентных штаммов микроорганизмов.

Mammals and birds are the primary hosts for numerous species of bloodsucking flies (Diptera: Hippoboscidae). These ectoparasites are involved in the circulation of a wide range of pathogens, including bacteria (Borrelia, Bartonella, Rickettsia, Anaplasma, Ehrlichia), protozoa (Trypanosoma, Theileria, Piroplasmida, Haemosporida), and viruses (in particular, West Nile virus). Hippoboscids are obligate ectoparasites, and prolonged exposure to host pathogens has evolved highly effective "natural antibiotics"— antimicrobial peptides (AMPs)—in their bodies. This article summarizes current information on pathogens associated with hippoboscids and substantiates the need for further study of bioecological aspects, including the species composition, distribution, and abundance of bloodsuckers. Laboratory monitoring of this group of insects is important for understanding the mechanisms of preservation and spread of natural focal infections that are dangerous to humans and animals. Attention is also paid to the antimicrobial peptides (AMPs) of insects and their activity against antibiotic-resistant strains of microorganisms.

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The authors declare that there are no conflicts of interest present.