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Some epigenetic aspects of the mechanisms of antigenic variability of malarial parasites

https://doi.org/10.33092/0025-8326mp2024.4.52-56

Abstract

The article presents current data on the study of genetic adaptations in the parasite-host system in human malaria. In particular, the work is devoted to the analysis of some epigenetic mechanisms of antigenic variability of plasmodia, that ensure their survival and adaptation in the host organism. Understanding of these mechanisms may provide insights into the development of new strategies for the treatment and prevention of malaria.

About the Authors

T. V. Sakharova
Sechenov First Moscow State Medical Univesity, Department of Biology and General Genetics
Russian Federation

Moscow



S. N. Larina
Sechenov First Moscow State Medical Univesity, Department of Biology and General Genetics
Russian Federation

Moscow



V. M. Rakova
Federal State Budgetary Educational Institution of Higher Education “Moscow state Academy of Veterinary Medicine and Biotechnology - MVA by K.I. Skryabin”; RMA of Continuous Professional Education
Russian Federation

Moscow



V. B. Poluektova
Sechenov First Moscow State Medical Univesity, Department of Biology and General Genetics
Russian Federation

Moscow



E. D. Ivanova
Sechenov First Moscow State Medical Univesity, Department of Biology and General Genetics
Russian Federation

Moscow



S. S. Malin
Sechenov First Moscow State Medical Univesity, Department of Biology and General Genetics
Russian Federation

Moscow



Y. V. Shidlovskii
Sechenov First Moscow State Medical Univesity, Department of Biology and General Genetics
Russian Federation

Moscow



N. V. Chebyshev
Sechenov First Moscow State Medical Univesity, Department of Biology and General Genetics
Russian Federation

Moscow



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Review

For citations:


Sakharova T.V., Larina S.N., Rakova V.M., Poluektova V.B., Ivanova E.D., Malin S.S., Shidlovskii Y.V., Chebyshev N.V. Some epigenetic aspects of the mechanisms of antigenic variability of malarial parasites. Medical Parasitology and Parasitic Diseases. 2024;(4):52-57. (In Russ.) https://doi.org/10.33092/0025-8326mp2024.4.52-56

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ISSN 0025-8326 (Print)
ISSN 2713-1777 (Online)